Filitra Professional 20 mg – Vardenafil 20 mg Tablets Cos
Filitra Professional Pharmacokinetics
Filitra Professional, comprising vardenafil 20mg, is a potent phosphodiesterase type 5 (PDE5) inhibitor. It efficiently boosts blood flow to facilitate erectile function. Vardenafil is absorbed swiftly, with peak plasma concentration occurring approximately 60 minutes post-ingestion. Its bioavailability is about 15%, due to first-pass metabolism. The substance exhibits a half-life of 4-5 hours, allowing for sustained therapeutic action.
The metabolism of Filitra Professional occurs predominantly in the liver, primarily via CYP3A4, with minor involvement from CYP3A5 and CYP2C9. Vardenafil is highly protein-bound (approximately 95%), leading to a significant reduction in free drug available for distribution. Excretion is primarily through fecal elimination, with a small percentage renally excreted.
Dosage Information
Filitra Professional is available in an oral formulation of vardenafil 20mg. The recommended starting dose is 10 mg, tailored to patient response and tolerability. Adjustments, if necessary, should be made cautiously. The maximum recommended dose is 20 mg, with a frequency not exceeding once per day. It is crucial to administer the tablet orally with water, ideally an hour before sexual activity.
Factors such as age, liver function, and concomitant medications may necessitate dose adjustments. Elderly patients or those with hepatic impairment should initiate treatment at lower doses. Patients should avoid fatty meals when taking the medication, as this can impede absorption and delay efficacy.
Filitra Professional Contraindications
Filitra Professional is contraindicated in patients with known hypersensitivity to vardenafil. It is unsuitable for individuals with severe cardiovascular disorders, including recent myocardial infarction or stroke. Concomitant use with nitrates or nitric oxide donors is strictly prohibited due to the risk of profound hypotension.
Patients with retinal disorders such as retinitis pigmentosa should avoid this medication. Individuals with severe hepatic impairment or end-stage renal disease should not use Filitra Professional. Caution is advised in those with anatomical penile deformities or predisposition to priapism.
Pregnancy and Breastfeeding
Filitra Professional, primarily indicated for erectile dysfunction, has no application in women. However, if inadvertent exposure occurs, limited data suggests no direct teratogenic effects. Its use during pregnancy remains unjustified due to the absence of therapeutic benefits.
Lactation studies are nonexistent, given the drug’s target population. The lack of evidence on secretion into breast milk further supports its inapplicability for breastfeeding women. Healthcare providers must guide their patients, ensuring awareness of the drug’s intended demographic.
Filitra Professional Adverse Effects
Adverse effects associated with Filitra Professional are generally mild to moderate. Commonly reported reactions include headache, flushing, nasal congestion, and dyspepsia. Rare but serious side effects involve visual disturbances and sudden hearing loss.
Some users may experience dizziness, exacerbated by alcohol consumption or antihypertensives. Priapism, although rare, requires immediate medical attention to prevent long-term damage. Patients must report persistent or troublesome symptoms to their healthcare provider promptly.
Filitra Professional For Sale
Filitra Professional is available for purchase at pharmacies with a valid prescription. Online platforms also offer the medication, but buyers should exercise caution. Authenticity and regulatory compliance are paramount when purchasing pharmaceuticals via the internet.
Pricing can vary based on location and retailer. Bulk purchases may provide cost advantages, although efficacy and safety should never be compromised for price. Patients are advised to consult healthcare professionals to ensure the suitability and safe use of Filitra Professional.
Pharmacokinetics | Dosage | Adverse Effects |
---|---|---|
Absorption: Rapid | Initial: 10 mg | Headache, Flushing |
Peak: ~60 mins | Max: 20 mg/day | Dizziness, Visual Disturbances |